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Supplements and Blood Thinners: The Cautions Sources List for SodaPeak's Names
Some supplements can interact with blood thinners. Memorial Sloan Kettering says saw palmetto may increase bruising and bleeding with warfarin and other blood thinners and may add to antiplatelet drugs and NSAIDs, with serious bleeding case reports. SodaPeak lists saw palmetto. Anyone on a blood thinner should show a prescriber the full label first.
Written by the SodaPeak label deskUpdated · 4 min read

The caution01
What does MSK say about saw palmetto and bleeding?
That it may increase bruising and bleeding with warfarin and other blood thinners.
MSK also says it may add to antiplatelet drugs and NSAIDs, and lists serious case reports including pericardial bleeding in a person on a blood thinner and bleeding during surgery (MSK, Saw Palmetto). These are case reports, not rates, and a prescriber weighs them against your own situation.
| Name | Caution |
|---|---|
| Saw palmetto | Blood thinners, antiplatelets, NSAIDs |
| Horny goat weed | CYP3A4 medicines, aromatase inhibitors (MSK, Epimedium) |
| Nettle | Blood pressure medicines, diuretics, CYP450 medicines (animal data) (MSK, Nettle) |
| Sarsaparilla | CYP3A4 and CYP2D6 medicines (MSK, Smilax glabra) |
Tell them02
Whom do I tell?
Every health care provider, and your pharmacist.
NCCIH says to tell all your health care providers about every supplement you take, because supplements can interact with prescription and over-the-counter medicines (NCCIH, Using Supplements Wisely). A pharmacist can check the list for interactions in minutes.
Names on the SodaPeak label that a source flags:
- Horny goat weed
- Tongkat ali
- Saw palmetto
- Nettle root
- Wild yam
- Sarsaparilla
- Orchic substance
- Boron amino acid chelate
MSK says saw palmetto may increase bruising and bleeding with warfarin and other blood thinners, may add to antiplatelet drugs such as clopidogrel, and may add to the side effects of NSAIDs. It also lists serious bleeding case reports.
Interaction notes from (NCCIH, Saw Palmetto) (MSK, Saw Palmetto) (MSK, Epimedium) (NIDDK LiverTox, Tongkat Ali) (MSK, Nettle) (MSK, Wild Yam) (MSK, Smilax glabra) (RxList, Orchic Extract). Not a complete list. The label prints no amounts for these names, so nobody can say how strong any effect would be. Ask your pharmacist with the bottle in hand, and never stop or change a prescribed medicine on your own.
Warning signs03
What are signs of a bleeding problem?
Unusual bruising, nosebleeds that will not stop, black stools or blood in urine.
Any of these needs prompt medical advice. Heavy bleeding, chest pain or fainting is an emergency: call 911. The side effects page lists more signs.

SodaPeak Capsules: 60 per bottle30 servings of 2 capsules · 1, 2, 3 or 6 bottles · price shown at checkout
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FAQ05
SodaPeak questions people ask
Can saw palmetto interact with blood thinners?
MSK says it may increase bruising and bleeding with warfarin and other blood thinners.
Does SodaPeak contain saw palmetto?
Yes, saw palmetto extract is the third name on the label.
Who should I tell?
Every provider and your pharmacist.
What are signs of bleeding?
Unusual bruising, nosebleeds that will not stop, black stools or blood in urine.
Who wrote this06
Written and reviewed by
Pages built from the label, the seller brief and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is the information site for a USA Authorized SodaPeak Retailer. It is not the manufacturer, and it does not name one. We earn money when you buy through our order links.
Sources and links (9)
- Saw Palmetto (About Herbs) Memorial Sloan Kettering Cancer Center, 2023
- Epimedium (horny goat weed), About Herbs Memorial Sloan Kettering Cancer Center, 2023
- Nettle (About Herbs) Memorial Sloan Kettering Cancer Center, 2021
- Smilax glabra (Tufuling), About Herbs Memorial Sloan Kettering Cancer Center, 2022
- Using Dietary Supplements Wisely National Center for Complementary and Integrative Health (NIH), 2019
- Saw Palmetto National Center for Complementary and Integrative Health (NIH), 2025
- Tongkat Ali (LiverTox) NIDDK, LiverTox database, 2024
- Wild Yam (About Herbs) Memorial Sloan Kettering Cancer Center, 2022
- Orchic Extract RxList, 2026
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